Captain Underpants and the Attack of the Talking Toilets is a comic by Treehouse Comix Inc., Written by George Beard and Illustrated by Harold Hutchins. It appears in Captain Underpants and the Attack of the Talking Toilets. After making the book and due to so many staff members in the teachers lounge, George and Harold tried to make copies of the book with Melvin's PATSY 2000. Unfortunately they did not believe anything Melvin said and since anything on the PATSY's surface will be turned alive and 3 dimensional this caused the Talking Toilets and the Turbo Toilet 2000 on the front of the comic book to come to life.
The comic in the book starts with another normal day at school until a UFO appears and shoots the school with a ray. This ray causes the toilets to come to life and make them evil. They then start eating everyone in the school (including, to nobody's dismay, the Gym Teacher. They also scratched somebody's car during the carnage). Captain Underpants appears and runs to the storage room. He finds a bunch of plungers and places them in the toilets' mouths, so they cannot eat anymore. Captain Underpants then goes out to stop the UFO.
Once he approaches it, it opens up and The Turbo Toilet 2000 appears to fight him. A fight begins shortly after. Capt. Underpants wins by giving the T.T. 2000 a wedgie and placing it on a stop sign. The T.T. 2000 is aimed and fired at the UFO, causing them both to explode. Everything goes back to normal as the comic ends; even the gym teacher escapes, much to everyone's disappointment.