As mentioned before, he is a scientist who spends most of his time conducting experiments. He is very dedicated to his work as he barely pays his son any attention as shown when he paid no mind to his promise of revenge in George and Harold.
Despite that, he truly loves his son as he was happy to see he was alright after he was chased by the bionic robot boogers.
When Melvin turns into The Bionic Booger Boy, he gets defeated by Sulu the Bionic Hamster. Mr. Sneedly takes George's advice by switching the batteries in the Combine-O-Tron 2000 so that Melvin can return to normal. It takes 2 blasts from the Combine-O-Tron 2000 to separate things. Also, before Melvin transforms himself with Combine-O-Trom 2000, it shows him and his wife doing a secret experiment for the government, which apparently included Pop Rocks.